Distress Related to Attenuated Psychotic Symptoms: Static and Dynamic Association With Transition to Psychosis, Nonremission, and Transdiagnostic Symptomatology in Clinical High-Risk Patients in an International Intervention Trial.

Barnaby Nelson; Hok Pan Yuen; G Paul Amminger; Gregor Berger; Eric YH Chen; Lieuwe de Haan; Jessica A Hartmann; Ian B Hickie; Suzie Lavoie; Connie Markulev; Nilufar Mossaheb; Dorien H Nieman; Merete Nordentoft; Andrea Polari; Anita Riecher-Rössler; Miriam R Schäfer; Monika Schlögelhofer; Stefan Smesny; Amy Tedja; Andrew Thompson; Swapna Verma; Alison R Yung; Patrick D McGorry

Journal article

Distress Related to Attenuated Psychotic Symptoms: Static and Dynamic Association With Transition to Psychosis, Nonremission, and Transdiagnostic Symptomatology in Clinical High-Risk Patients in an International Intervention Trial.

Barnaby Nelson, Hok Pan Yuen, G Paul Amminger, Gregor Berger, Eric YH Chen, Lieuwe de Haan, Jessica A Hartmann, Ian B Hickie, Suzie Lavoie, Connie Markulev, Nilufar Mossaheb, Dorien H Nieman, Merete Nordentoft, Andrea Polari, Anita Riecher-Rössler, Miriam R Schäfer, Monika Schlögelhofer, Stefan Smesny, Amy Tedja, Andrew Thompson Show all

Schizophr Bull Open | Published : 2022

DOI: 10.1093/schizbullopen/sgaa006

Abstract

This study examined whether distress in relation to attenuated psychotic symptoms (DAPS) is associated with clinical outcomes in an ultra-high risk (UHR) for psychosis sample. We also investigated whether DAPS is associated with cognitive style (attributional style and cognitive biases) and whether amount of psychosocial treatment provided is associated with reduction in DAPS. The study was a secondary analysis of the "Neurapro" clinical trial of omega-3 fatty acids. Three hundred and four UHR patients were recruited across 10 early intervention services. Data from baseline assessment, regular assessments over 12 months, and medium term follow-up (mean = 3.4 years) were used for analysis. Fi..

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